Friday, January 9, 2015

Fwd: Alzheimers

'Researchers around the world keep looking for ways to limit the memory damage caused by Alzheimer's disease.  The latest treatment showing some promise is a nasal spray that uses a form of the insulin hormone.

For 21 days, a team of scientists at Wake Forest Baptist Medical Center monitored the effects of manufactured insulin on 60 adults with either mild cognitive impairment (MCI) or moderate Alzheimer's dementia (AD). One group was given 40 units of the nasal insulin detemir, another was given 20 units and a third group was given a placebo.

Of the three groups, short-term ability to process verbal and visual cues increased the most in those who were given 40 units of the spray. That same dosage of the spray was also able to increase memory scores for those carrying the gene that increases a person's risk for dementia the most. Carrying that particular gene usually makes the body resistant to most treatments.'

http://www.healthcentral.com/dailydose/cf/2015/01/9/insulin_nasal_spray_boosts_memory_in_study


I already forgot what the article is about.  

 

Thursday, January 8, 2015

Fwd: Longevity

'Bowhead whales are most likely the longest-living mammals on the planet. There's evidence (some of it in the form of Victorian-era harpoons embedded in blubber) that they can live as long as 200 years. And there are humans who'd like to get a little slice of that longevity for themselves.

This week, some of them took the first step to stealing the bowhead whale's secrets: They sequenced its genome. Their results were published Tuesday in Cell.

"I think that having the genome sequence of the bowhead whale will allow researchers to study basic molecular processes and identify maintenance mechanisms that help preserve life, avoid entropy and repair molecular damage," said corresponding author Joao Pedro de Magalhaes of the University of Liverpool.'

http://www.washingtonpost.com/news/speaking-of-science/wp/2015/01/06/researchers-hope-this-whales-genes-will-help-reverse-human-aging/

 


Fwd: Antibiotic

'The decades-long drought in antibiotic discovery could be over after a breakthrough by US scientists…

The last new class of antibiotics to make it to clinic was discovered nearly three decades ago.

The study, in the journal Nature, has been described as a "game-changer" and experts believe the antibiotic haul is just the "tip of the iceberg".

The heyday of antibiotic discovery was in the 1950s and 1960s, but nothing found since 1987 has made it into doctor's hands.

Since then microbes have become incredibly resistant. Extensively drug-resistant tuberculosis ignores nearly everything medicine can throw at it.

Back to soil

The researchers, at the Northeastern University in Boston, Massachusetts, turned to the source of nearly all antibiotics - soil.

This is teeming with microbes, but only 1% can be grown in the laboratory.

The team created a "subterranean hotel" for bacteria. One bacterium was placed in each "room" and the whole device was buried in soil.

It allowed the unique chemistry of soil to permeate the room, but kept the bacteria in place for study.

'

http://www.bbc.com/news/health-30657486


Fwd: Law

'Striking a blow for the freedom to eat the bloated livers of ducks and geese force-fed grain through tubes, a federal judge invalidated California's 2012 ban of foie gras.

http://www.allgov.com/usa/ca/news/top-stories/federal-judge-jokingly-strikes-down-state-foie-gras-ban-that-runs-afoul-of-us-law-150108?news=855312

So California cannot ban something Federal law allows….Colorado can allow something Federal law bans….and Arizona cannot pass a law identical to federal law to ban the same thing federal law does.

Saturday, December 27, 2014

Fwd: memory

'New research indicates that lost memories can be restored, according to new research into a type of marine snail called Aplysia. The findings offer some hope for patients in the early stages of Alzheimer's disease'

Tuesday, December 23, 2014

lifespan

'A common over-the-counter drug that tackles pain and fever may also hold keys to a longer, healthier life, according to a Texas A&M AgriLife Research scientist.

Regular doses of ibuprofen extended the lifespan of multiple species, according to research published in the journal Public Library of Science, Genetics.

"We first used baker's yeast, which is an established aging model, and noticed that the yeast treated with ibuprofen lived longer," said Dr. Michael Polymenis, an AgriLife Research biochemist in College Station. "Then we tried the same process with worms and flies and saw the same extended lifespan. Plus, these organisms not only lived longer, but also appeared healthy."

He said the treatment, given at doses comparable to the recommended human dose, added about 15 percent more to the species lives. In humans, that would be equivalent to another dozen or so years of healthy living.

http://www.sciencedaily.com/releases/2014/12/141218141004.htm


Tuesday, December 16, 2014

Fwd: Glycemic index

'Some studies have suggested that carbs with a low glycemic index—such as whole grains—led to fewer spikes in blood sugar, and therefore more efficient breakdown into energy, while higher glycemic index foods—including refined flours—led to larger peaks in glucose that the body couldn't process and therefore stored as fat.

So two of the diets in the study were high in carbs overall, but one was made up of low-glycemic-index foods while the other was composed of high-glycemic-index foods. The other two diets were low in carbs overall, with the same breakdown or low- and high-glycemic items

​...​

In fact, among those eating the high-carb diets, those consuming low-glycemic-index foods had worse insulin response and higher LDL cholesterol…

we did not show that the glycemic index of the carb really had any favorable effect," says Sacks.

That suggests that all the attention to knowing the glycemic index of various foods—and basing your eating habits on these numbers—may not be worth the effort.'

​...

Overall, those eating the low-carb diets had lower risk factors for heart disease compared to the group eating more carbohydrates, but the type of carbs didn't seem to make much difference​

http://time.com/3636690/glycemic-index-heart-health-low-carb/


Fwd: Malaria

'An international research collaborative has determined that a promising anti-malarial compound tricks the immune system to rapidly destroy red blood cells infected with the malaria parasite but leave healthy cells unharmed. 

Fwd: Ebola

'Endless Ebola Endemic? That's The 'Risk We Face Now,' CDC Says

Speed. That's key to ending the Ebola epidemic, says the director of the U.S. Centers for Disease Control and Prevention.

Dr. Thomas Frieden is visiting West Africa this week to figure out how to reduce the time it takes to find new Ebola cases and isolate them.

Otherwise, Ebola could become a permanent disease in West Africa.

http://www.npr.org/blogs/goatsandsoda/2014/12/15/370446566/endless-ebola-endemic-thats-the-risk-we-face-now-cdc-says

 

 

Tuesday, December 9, 2014

Fwd: Cancer

'Simple blood test could detect breast cancer long before symptoms appear - and spell the end of the mammogram 


A metal-detecting blood test that can give vital early warning of breast cancer is being developed by Oxford University scientists.

They hope the inexpensive and simple test will spot the disease long before a woman develops a lump – and say it could be used in a national screening programme.

Picking up the cancer at the earliest stages when it is easiest to treat could save thousands of lives, as well as spare patients and their loves ones the pain and distress of prolonged illness.

Researcher Fiona Larner said: 'Prevention is better than cure.

'There is a survival rate of about 80 per cent for breast cancer but the earlier you can detect it, the more chance you have of treating it.

http://www.dailymail.co.uk/health/article-2867188/Simple-blood-test-detect-breast-cancer-long-symptoms-appear-spell-end-mammogram.html#ixzz3LRJSFQ1k


Wednesday, October 29, 2014

Fwd: Google looking for cancer

'Google Inc. is designing tiny magnetic particles to patrol the human body for signs of cancer and other diseases, in the latest example of the Internet giant's sweeping ambition.

 

Google said its nanoparticles, less than one-thousandth the width of a red blood cell, would seek out and attach themselves to cells, proteins or other molecules inside the body. The company also is working on a wearable device with a magnet to attract and count the particles, as a monitoring tool.

 

The goal is to provide an early warning system for cancer and other diseases, with an eye toward more effective treatment.

 

"Every test you ever go to the doctor for will be done through this system," said Andrew Conrad, head of the Life Sciences team at the Google X research lab, who disclosed the project on Tuesday at The Wall Street Journal's WSJD Live conference. "That is our dream."'

 

http://online.wsj.com/articles/google-designing-nanoparticles-to-patrol-human-body-for-disease-1414515602

Monday, October 27, 2014

Fwd: Ebola

'The missteps and delays in diagnosis of the Liberian man prompted some states to impose or consider restrictions on travelers coming from the West African countries where the virus has killed nearly 5,000 people.


Responding to concerns that mandatory quarantine would inhibit doctors and nurses from traveling to West Africa, Cuomo said New York wanted to encourage personnel to go, lauding their "valor" and "compassion," while also protecting public safety at home.


"These people are extraordinary for their valor and their courage and their compassion," Cuomo said. "Anything we can do to encourage it, we want to do."

 

He added that New York was not changing the policy announced on Friday.

 

http://www.reuters.com/article/2014/10/27/us-health-ebola-usa-newyork-idUSKBN0IG12920141027

 

Monday, October 13, 2014

Fwd: Ebola

Technologies like this allow us to imagine a new form of quarantine. Rather than relying on primitive instruments, indiscriminate profiling or questionnaires, we should consider running a pilot program to test asymptomatic travelers using sensitive P.C.R.-based techniques. Obviously, such technologies are expensive, but the cost is not prohibitive. A typical P.C.R. reaction, including labor, costs between $60 and $200 (we have already spent 100 times more disposing of the contaminated sheets from the home Mr. Duncan stayed in). Since the test takes about a third of the time of a trans-Atlantic flight, the flight would become the quarantine.

 

Huge logistical questions would need to be solved. Where would such a screening test be administered — before departure from West Africa, or upon landing? Could we imagine a walking quarantine in which travelers were granted provisional entry, but recalled if they tested positive? What infection precautions would need to be in place for such testing? What forms of consent would be required? Who would bear the costs? Who exactly would be tested?'

 

http://www.nytimes.com/2014/10/13/opinion/how-to-quarantine-against-ebola.html?_r=0

 

Thursday, October 2, 2014

Fwd: Ebola

'Dr. Gavin MacGregor-Skinner, a specialist in treating Ebola, sounded the alarm today on CNN about how ill-prepared U.S. customs is when dealing with visitors from Ebola-stricken areas.

 

MacGregor-Skinner, an ‎Assistant Professor, Department of Public Health Sciences at Penn State University, International Development Consultant, told Jake Tapper about how dangerous Ebola is.

 

    "When my team was in Nigeria and we were treating Ebola patients the first thing they said to me was 'Should we tell the truth?' 'Yeah when you come back we're telling the truth.'

 

    As we flew out of Nigeria I had my temperature taken and I was interviewed twice. As I came through Germany I had my temperature taken I was interviewed and questions were asked 'Where have you been? What have you done?'

 

    When I got back to Washington D.C. I said 'I've been working with Ebola patients." I was told 'Welcome back. Off you go!' No one took my temperature. No one asked me any questions. So we told the truth. There was no process, there was no program here to make sure we were OK."'

 

http://gotnews.com/video-ebola-doc-one-asked-questions-dc-customs/


But the system has its limits, relying on the traveler to reveal whether he or she has been exposed. And it leaves it to local officials to conduct the screening as they see fit, Dr. Cohen said. It is unclear how consistently or effectively those screenings are conducted across West Africa, and Dr. Cohen said she did not know how many potential travelers had been caught by screeners — if any.

 

"Our expectation is that people who are sick or people who are exposed should be getting the message they shouldn't be traveling."'

 

http://www.nytimes.com/2014/10/02/us/man-in-us-with-ebola-had-been-screened-to-fly-but-system-is-spotty.html?_r=0