Monday, November 29, 2010

FW: Discovery Health "Caffeine and Adenosine"

"The problem with caffeine is the longer-term effects, which tend to
spiral. For example, once the adrenaline wears off, you face fatigue and
depression. So what are you going to do? You consume more caffeine to
get the adrenaline going again. As you might imagine, having your body
in a state of emergency all day long isn't very healthy, and it also
makes you jumpy and irritable.

The most important long-term problem is the effect that caffeine has on
sleep. Adenosine reception is important to sleep, and especially to deep
sleep. The half-life of caffeine in your body is about six hours. That
means that if you consume a big cup of coffee with 200 mg of caffeine in
it at 3:00 p.m., by 9:00 p.m. about 100 mg of that caffeine is still in
your system. You may be able to fall asleep, but your body will probably
miss out on the benefits of deep sleep."

Monday, November 15, 2010

Artificial Sweeteners Make You Fat by Dr. Gary Huber

Can Sugar Substitutes Make You Fat? - TIME,8599,1711763,00.html

Diet Sweeteners Can Make You Sick and Fat

Sweet-taste receptors, low-energy sweeteners, gluc... [Br J Nutr. 2010] - PubMed result

 These studies have given rise to major speculations that the ingestion of food and beverages containing low-energy sweeteners may act via these intestinal mechanisms to increase obesity and the metabolic syndrome due to a loss of equilibrium between taste receptor activation, nutrient assimilation and appetite. However, data from numerous publications on the effects of low-energy sweeteners on appetite, insulin and glucose levels, food intake and body weight have shown that there is no consistent evidence that low-energy sweeteners increase appetite or subsequent food intake, cause insulin release or affect blood pressure in normal subjects. 

Monday, November 1, 2010

DNA and replacement organs

From: Trout, Larry R @


One of the biggest benefits from the continuing plunge in DNA testing costs is going to be earlier diagnosis of cancers. One DNA test under development for colon cancer detection will be usable at home...


Since some cancers develop literally over almost 2 decades early diagnosis opens up the potential of finding and removing cancers long before they become life threatening. Once home tests of blood and saliva for DNA (and likely for antigens) to detect cancer become cheap and widely available the challenge is going to be to find the early stage cancers. Early stage means they will be small. How to find them?

If the tests can narrow down the cancer source to a single organ then excising the cancerous tissue might not be continue to be necessary. Eventually we'll be able go in for new replacement organs. If a test could, for example, indicate presence of a pancreatic cancer 10 years before it will metastasize then in 2030 the solution might be to start growing a new one in a lab. Get the new one after 6 months or a year and toss out the old one.